Chemotherapeutics-Induced Intestinal Mucositis: Pathophysiology and Potential Treatment Strategies
نویسندگان
چکیده
منابع مشابه
Cancer Treatment-Induced Mucositis Pain: Strategies for Assessment and Management
Mucositis pain is a major clinical problem associated with cancer treatment. Mucosal tissue injury is a dose-limiting side effect and also limits nutritional intake and oral function, resulting in weight loss and nutritional deficits for many patients. The pathophysiology of mucositis is thought to be a complex array of cytokine-mediated events, which begins with mucosal atrophy and eventually ...
متن کاملCancer treatment-induced oral mucositis.
Oral mucositis is one of the main complications in non-surgical cancer treatments. It represents the major dose-limiting toxicity for some chemotherapeutic agents, for radiotherapy of the head and neck region and for some radiochemotherapy combined treatments. Many reviews and clinical studies have been published in order to define the best clinical protocol for prophylaxis or treatment of muco...
متن کاملAlzheimer's Disease: Pathophysiology, Hypotheses and Treatment Strategies
1 © Under License of Creative Commons Attribution 3.0 License | This article is available from: www.psychopathology.imedpub.com Alzheimer's disease (AD) is an irreversible, progressive neurodegenerative disorder. One new case of AD is expected to be developed every 33 seconds. So, about million new cases will be developed per year and the total estimated prevalence is expected to reach 13.8 mil...
متن کاملContrast-induced nephropathy: pathophysiology and preventive strategies.
Contrast-induced nephropathy is the third most common cause of hospital-acquired renal failure, after decreased renal perfusion and nephrotoxic medications. Identification of patients at risk and implementation of preventive strategies can decrease the incidence of this nephropathy. Prevention strategies focus on counteracting vasoconstriction, enhancing blood flow through the nephron, and prov...
متن کاملOral and Gastrointestinal Mucositis: Novel Insights into Pathophysiology and Potential Therapies
Mucositis is a dose-limiting side effect of highdose chemotherapy and radiotherapy currently used in many cancer treatments and in the intensive conditioning that precedes hematopoietic stem cell transplantation (HSCT). Increasing awareness of the clinical and economic consequences of mucositis and ongoing research into the molecular and cellular mechanisms of mucositis have spurred development...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Frontiers in Pharmacology
سال: 2021
ISSN: 1663-9812
DOI: 10.3389/fphar.2021.681417